Ana sayfa | MS’in Derinliği  | MS Slide Resource

Foreword

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system. The highly variable clinical expression of multiple sclerosis is due, in essence, to the destruction of myelin sheaths, which are responsible for insulating impulse conducting fibres. Their destruction impairs or blocks conduction along nerve fibres in the brain and spinal cord.

The following text summarizes recent evidence showing how the immune system is involved in the formation of demyelinating lesions, and how the central nervous system tries to repair that damage. At the end, an attempt is made to place all the different pathogenetic mechanisms into a general concept of multiple sclerosis pathogenesis.

  Hans Lassmann

Guest editor

Dr Hans Lassmann graduated in medicine from the University of Vienna in 1975. He trained in Neuropathology at the Neurological Institute of the University of Vienna. From 1977 to 1978 he was a visiting scholar at the New York State Institute for Basic Research in Developmental Disabilities. He has worked for many years on the neuropathology and neuroimmunology of multiple sclerosis, serves on numerous editorial boards, and is the author or co-author of some 200 scientific papers.

Dr. Lassmann's main interest has been to unravel the principal mechanisms of immune surveillance, inflammation, tissue damage and demyelination in the nervous system. A major focus of his research has been to define how these principal neuroimmunological mechanisms are reflected in the immunopathology of multiple sclerosis.

Produced as an educational service from Schering AG.

First Edition 1995.

The opinions expressed in this educational programme are not necessarily those of Schering AG.

©1995 Schering AG. All rights reserved, including that of translation into other languages. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval systems, without permission from Schering AG.

Bu sayfadaki bilginin en son güncellendiği/doğrulandığı tarih:

11/09/2001

Ana sayfa | Bağlantılar | Kayıt ve geri bildirim | Sözlükçe | Arama motoru ve site haritası | Yerel Bilgiler | Yardım| Bir arkadaşa söyleyin | Sorumluluk almama | Basın Bilgileri | Schering